Restriction of the feed antibiotics in the diet of farm animals formed a new economical and research challenge: a necessity for new feed additives which are able to provide immunomodulating effects. The review summarizes some international experience with the application of immunomodulating feed additives. There are numerous species/strains of fungi which could serve as immunomodulators. According to the known data, fungal activity has been established and well-known; however, till the present time, fungal preparations are not widespread because their production is complicated, time-consuming, and expensive. In this brief essay, we present information on some immunomodulating fungal feed additives as well as show the possibility of fungal cultivation directly on feed substrates to combine the immunomodulating additives and feed as a waste-free organic whole.
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