Key result
Prior cardiac disease is linked to ~2.6-fold higher odds of abnormal maternal echocardiography.
Why the study?
Few obstetric-specific guidelines detail the indications for screening echocardiography in pregnancy and their association with abnormal findings and pregnancy management.
Cohort (n=195)
No
History of cardiac disease may guide echocardiography in low-risk pregnancies; supports ACCF criteria but leaves prospective validation open.
Objective Few obstetric-specific guidelines detail the indications for screening echocardiography in pregnancy. The objective of the study is to examine the association of common indications for maternal echocardiography with the likelihood of abnormality identification, pregnancy management alteration, and conformity with current American College of Cardiology Foundation (ACCF) guidelines. Study Design This retrospective cohort analysis categorized all echocardiograms performed within pregnancy and the first month postpartum within a tertiary health system to correlate indications with abnormal findings. Results Data from 226 echocardiograms were analyzed from 205 women. The most common indication for initial echocardiography was cardiac symptoms (34.6%). History of cardiac disease was the only indication demonstrating a significant association with an abnormal finding on initial echocardiography (odds ratio [OR]: 2.6; p = 0.006). Postpartum status (OR: 4.9; p < 0.001), multiparity (p < 0.001), and tobacco use (OR: 2.2; p = 0.011) were demographic characteristics associated with the identification of abnormal findings on initial echocardiography. Abnormal echocardiographic findings were associated with changes in clinical management but did not correlate with adverse obstetric or neonatal outcomes, which may support the impact of a multidisciplinary programmatic approach. ACCF appropriateness criteria correlated well with identification of abnormal echocardiographic results (p = 0.034). Conclusion Although the presence of cardiac symptoms or history of diabetes failed to demonstrate association with abnormal echocardiographic findings, a history of prior cardiac disease, tobacco use, multiparity, and postpartum status were factors associated with identification of abnormal findings on initial maternal echocardiography. The ACCF appropriateness criteria for obtaining echocardiography can be applied to pregnant women with consideration for these additional risk factors.
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Schnettler et al. (2021) conducted a cohort in Pregnancy in women without known high-risk structural heart disease (n=195). History of cardiac disease vs. No history of cardiac disease was evaluated on Abnormal finding on initial maternal echocardiography (OR 2.6, p=0.006). Among low-risk pregnant women, a history of prior cardiac disease was significantly associated with an abnormal finding on initial maternal echocardiography (OR 2.6).
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