Key result
High RDW shows no significant association with one-year mortality in anterior STEMI.
Why the study?
The diagnostic and prognostic value of red cell distribution width (RDW) in patients with anterior STEMI undergoing primary angioplasty and its relationship with hospital and one-year mortality was uncertain.
Does an elevated red cell distribution width (RDW) predict in-hospital and one-year mortality in patients with anterior ST-elevation myocardial infarction undergoing primary angioplasty?
Cohort (n=300)
No
Does an elevated red cell distribution width (RDW) predict in-hospital and one-year mortality in patients with anterior ST-elevation myocardial infarction undergoing primary angioplasty?
In patients with anterior STEMI undergoing primary angioplasty, an elevated RDW does not predict in-hospital or one-year mortality, but is significantly associated with an increased risk of adverse in-hospital complications.
Does not support RDW for mortality risk stratification in anterior STEMI; leaves open its utility for in-hospital complications.
Introduction and objective: The clinical diagnosis of acute myocardial infarction (MI) requires a rigorous assessment of the patient's medical history and with evidence of myocardial necrosis obtaind indirectly using biochemical, electrocardiographic, or imaging methods. Normally, the disorder of the blood supply to the coronary arteries and its disproportion with the needs of the myocardium leads to ischemia, hypoxia and finally necrosis of the myocardium. In almost all patients, the vascular pathology is atherosclerosis, usually associated with thrombosis and obstruction of one of the coronary arteries, and considering the increasing prevalence of ST-elevation myocardial infarction (STE-MI) and of healthcare costs and its clinical consequences, and the involvement various factors in the diagnosis of Ant patients STEMI In this study, we intend to investigate the diagnostic value of RDW in Ant STEMI patients as well as the effect of red cell distribution width (RDW) level on hospital and one-year mortality of patients diagnosed with Ant-STEMI who underwent primary angioplasty in Shahid Madani Hospital, Tabriz University of Medical Sciences so that we can evaluate them. The impact of the RDW level on the clinical outcome of these patients was determined and the necessary treatment decisions were made to improve the treatment outcome of these patients. Materials and Methods: With referring to the archive of Shahid Madani Tabriz Hospital heart Center, the list of patients diagnosed with Ant-STEMI in Shahid Madani Hospital of Tabriz University of Medical Sciences was compiled and assembled, in 2018-2019 underwent primary angioplasty. The inclusion and exclusion criteria were included in the study and reviewed. Results: In the conducted study, the amount of RDW with one-year mortality and non-hospital mortality was determined. There was no significant relationship, however, with hospital complications such as heart failure and cardiogenic shock. Angio hematoma, gastrointestinal bleeding and stent thrombosis had a significant relationship. Conclusion: We found that RDW is not a reliable prognostic factor for mortality in ant-STEMI patients.
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Bodagh et al. (2023) conducted a cohort in Anterior ST-Elevation Myocardial Infarction (Ant-STEMI) (n=300). High Red Cell Distribution Width (RDW > 12.75) vs. Normal Red Cell Distribution Width (RDW ≤ 12.75) was evaluated on One-year mortality (p=0.682). High red cell distribution width (>12.75) was not significantly associated with one-year mortality in patients with anterior ST-elevation myocardial infarction, though it correlated with in-hospital complications.
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