Answers are grounded in this paper and cite their sources.
The synthesis of a new class of peptidomimetics 1a-j, based on a 1,4-benzodiazepine scaffold and on a C-terminal aspartyl aldehyde building block, is described. Compounds 1a-j provided significant inhibitory activity against falcipains 2A and 2B (FP-2A and FP-2B), two cysteine proteases from Plasmodium falciparum.
No takes yet. Share an insight, caveat, or question.
Micale et al. (2006) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: