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OBJECTIVE: To statistically pool prevalence estimates of all studies on co-morbid psychiatric disorders in samples of opioid addicts. METHODS: 16 studies were identified which comprised 3754 opioid addicts. Meta-analysis was conducted using precision weighted algorithms. RESULTS: 78 % of the opiate addicts had at least one co-morbid psychiatric disorder at least once in their lifetime. Especially personality disorders had a high prevalence (42 %). The second highest prevalence was found with mood disorders (31 %), the third highest prevalence was anxiety disorders with 8 %. CONCLUSIONS: The high prevalence of psychiatric disorders among opioid addicts signaled the need to improve and develop better treatment programs.
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Frei et al. (2002) studied this question.