Key result
JCAD inactivation or post-ischemic silencing reduced brain ischemic lesion volume and improved neurological status in experimental models of acute ischemic stroke.
Why the study?
Does JCAD inactivation prevent ischemia/reperfusion-induced brain injury in experimental models of acute ischemic stroke?
Does JCAD inactivation prevent ischemia/reperfusion-induced brain injury in experimental models of acute ischemic stroke?
Answers are grounded in this paper and cite their sources.
Endothelial JCAD is a mediator of ischemia/reperfusion brain injury, and its targeted inhibition may offer a novel therapeutic strategy for neurovascular protection after acute ischemic stroke.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Zvonimir S. Katušić (2025) conducted an editorial in Acute ischemic stroke. JCAD inactivation (genetic or siRNA silencing) vs. Control was evaluated. JCAD inactivation or post-ischemic silencing reduced brain ischemic lesion volume and improved neurological status in experimental models of acute ischemic stroke.
Synapse has enriched 10 related papers. Consider them for comparative context: