An aqueous methanol extract of the Oriental crude drug “sohaku-hi”, the root barks of Morus alba , prominently reduced the plasma sugar level in mice. Activity-guided fractionation of the extract furnished a glycoprotein, moran A, which elicited remarkable hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.
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Hikino et al. (1985) studied this question.
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