Key result
Angina linked to ~50% higher 12-year mortality risk in women.
Why the study?
The prevalence and long-term mortality risk associated with angina in women aged 45-74 in south Wales were not well characterized.
Cohort (n=1,428)
No
Angina was associated with 50% higher mortality in women; hypothesis-generating and should not yet change practice.
The London School of Hygiene cardiovascular questionnaire was administered by interviewers in a community survey of 1428 women aged 45-74 living in the Rhondda Fach in south Wales. The results were analysed after a 12 year follow up for mortality. The prevalence of angina was similar to that of a Swiss population, where the method of administration of the questionnaire was similar. The risk of dying associated with angina was some 50% higher than that for women without angina, significant at the 5% level. The risk was greatest for women aged 45-54 when angina accounted for some 15% of deaths in the follow up period. Grade 2 angina was associated with a higher mortality from coronary heart disease, with more than double the risk. The overall risk of dying associated with angina did not appear to decline with time.
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Campbell et al. (1984) conducted a cohort in Angina (n=1,428). Angina vs. Women without angina was evaluated on Mortality (50% higher risk, p=<0.05). Angina was associated with an approximately 50% higher risk of 12-year mortality compared to women without angina (p<0.05).
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