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The emerging role of complex modifications of tRNALysUUU in signaling pathways – Coordination of cell growth with nutrient availability, in particular amino acids, is a central problem that has been solved by the implementation of complex regulatory cascades. Although the specific regulatory mechanisms differ between kingdoms and species, a common theme is the use of tRNA molecules as sensors and transducers of amino acid starvation. In many (...)
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Thiaville et al. (2015) studied this question.
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