Key result
Low BMI is linked to ~10-fold higher risk of poor composite outcomes after Micra implantation.
Why the study?
The effect of low BMI on the outcome of Micra leadless pacemaker implantation was not well studied, despite the investigational device exemption study population having a higher mean BMI.
Cohort (n=147)
No
Micra TPS implantation in low-BMI patients requires caution; leaves open the need for prospective safety data in this subgroup.
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Tam et al. (2022) conducted a cohort in Bradyarrhythmia (n=147). Low body mass index (<23.76 kg/m2) vs. Higher body mass index (≥23.76 kg/m2) was evaluated on Poor composite efficacy and safety outcome (failure to achieve successful implantation with low/stable thresholds or occurrence of major complications in the first year) (p=0.009). Micra leadless pacemaker implantation in patients with a low body mass index (<23.76 kg/m2) was associated with a significantly higher rate of poor composite efficacy and safety outcomes compared to those with a higher BMI (14% vs 1.4%, p=0.009).
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