Synthesis of Heterocyclic KeteneN,S-Acetals and Their Reactions with Esters of α,β-Unsaturated Acids

All articles of this category Ketene S,S -acetals 2 react with 2-amino-1-ethanethiol to afford the substituted 2-methylenethiazolidines 3 . The structure of these products as ketene N,S -acetals is confirmed by spectroscopic data. Compounds 3a-f react with esters of α,β-unsaturated acids to give thiazolo[3,2- a ] pyrid-5-one derivatives 4 , 6 , and 7 through an electrophilic addition and cyclocondensation sequences.