We introduce the design of a chip for the controlled adhesion of anchorage‐dependent cells. A hybrid copolymer, comprising the peptide cell‐recognition motif RGD, attached to a protein‐repellent poly(dimethylacrylamide) PDMAA polymer is used in a lithography process to implement a chemical microstructure on planar surfaces. The characterization of the surface‐attached film along with a first study of its performance in cell adhesion assays is presented. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
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Loschonsky et al. (2009) studied this question.
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