Sterol biosynthesis in the oyster,Crassostrea virginica, was examined by injection of [2‐14C]acetate and [2,3‐3H] lanosterol. The oyster incorporated [2‐14C] acetate into squalene 4,4′‐dimethylsterols, 4‐monomethylsterols, cholesterol, desmosterol, isofucosterol, and 24‐methylenecholesterol, and also converted [2‐3H] lanosterol to cholesterol. Therefore, the oyster was concluded to synthesize cholesterol, desmosterol, isofucosterol, and 24‐methylenecholesterol from acetate via squalene, probably using the lanosterol pathway.
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Teshima et al. (1981) studied this question.
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