Effectiveness of Non-benzodiazepine Antiepileptic Drugs in Benzodiazepine-resistant Convulsive Status Epilepticus

This is the authors' abstract. We don't add key points for this paper.

Time-dependent pharmacoresistance is a major therapeutic problem in SE and CSE. As seizures continue, pharmacoresistance develops progressively. The anti-seizure effectiveness of benzodiazepines could reduce 20-fold in 30 min of seizures. The objective of this study is to précis the existing proof that compares ‎ the effect of valproate, phenytoin, diazepam, ‎‎ phenobarbital, lacosamide, and levetiracetam on benzodiazepine-resistant convulsive status ‎‎ epilepticus. &l