Key result
Class I obesity in young adults is linked to ~3-point worse left ventricular GLS.
Why the study?
The clinical significance of Class I obesity in young adults without diagnosed disease remains uncertain, particularly regarding early myocardial function impairment.
Cross-Sectional (n=131)
Absolute Event Rate: -19% vs -21.8%
p-value: p=<0.001
In young adults without diagnosed disease, Class I obesity is associated with subclinical myocardial dysfunction as evidenced by impaired global longitudinal strain and left atrial reservoir strain, which correlate with visceral and epicardial adiposity.
May support earlier cardiac assessment in asymptomatic Class I obesity; leaves open whether intervention alters progression in young adults.
The clinical significance of Class I obesity (BMI: 30.0-34.9 kg/m²) in young adults without diagnosed disease remains uncertain.Although their BMI exceeds the threshold associated with increased cardiovascular risk, these individuals often receive only general lifestyle advice.The author assessed whether myocardial function is already impaired at this stage.
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Alieva et al. (2026) conducted a cross-sectional in Class I obesity (n=131). Class I obesity (BMI 30.0-34.9 kg/m²) vs. BMI <30 kg/m² was evaluated on Left ventricular global longitudinal strain (GLS) (p=<0.001). Class I obesity in young adults without diagnosed disease was associated with impaired myocardial function, demonstrated by a reduced left ventricular global longitudinal strain of -19.0% compared to -21.8% in individuals with a BMI <30 kg/m².
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