Key result
The myocardial infarction standardized mortality rate using the 2013 European standard (44.5 per 100,000) was significantly higher than the 1976 standard (27.6 per 100,000, p<0.0001).
Why the study?
The impact of different estimation methods on myocardial infarction mortality rates and regional variability interpretation was unclear.
Cross-Sectional (n=82)
Absolute Event Rate: 44.5% vs 27.6%
p-value: p=<0.0001
The choice of standard population (EU-1976 vs EU-2013) for calculating age-standardized mortality rates significantly alters regional myocardial infarction mortality statistics and rankings.
MI mortality rates and rankings differ by standardization standard; leaves open optimal reference for consistent regional comparisons.
Aim. To assess the impact of estimation methods on myocardial infarction (MI) mortality rates and discuss the interpretation of regional variability. Material and methods. Based on Rosstat data for 2023 on the average annual population and MI-related mortality in one-year age groups in 82 regions with a computer program (state registration number 216661114), non-standardized (non-SMR) and standardized mortality rates (SMR) were determined using the European Standard Population from 1976 (EU-1976) and 2013 (EU-2013). Results. The regional average SMR value (EU-1976) from MI was lower (27,6±14,1 per 100 thousand population) than the non-SMR (35,9±17,6) and SMR (EU-2013) 44,5±21,9 (pairwise differences are significant p<0,0001). In all regions, the SMR (EU-2013) is higher than the non-MR and SMR (EU-1976). When comparing regions according to SMR (EU-1976) and SMR (EU-2013), the rank did not change in 18 regions, while in 28 regions it improved and in 36 it worsened. The following most significant changes were identified: Arkhangelsk (shift from 58 th ranking place to 67 th ) and Sakhalin region (from 63 rd to 51 st ). Changes in the rank and value of the SMR are influenced by both the demographic composition of the population and the mortality rate in 5 year age groups. Conclusion. In all regions, the MI-related SMR (EU-2013) is higher than the SMR (EU-1976). Differences between regional SMR according to the new and old standards affect the region rank in terms of mortality from MI. The closer the regional age distribution of the population is to the EU-1976 or EU-2013 standard, the less the SMR changes compared to the non-SMR. Approaches to calculating population mortality from MI should be taken into account when assessing and ranking regions.
No takes yet. Share an insight, caveat, or question.
Samorodskaya et al. (2026) conducted a cross-sectional in Myocardial infarction (n=82). Standardized mortality rate using the 2013 European Standard Population (EU-2013) vs. Standardized mortality rate using the 1976 European Standard Population (EU-1976) was evaluated on Regional average myocardial infarction mortality rate per 100,000 population (p=<0.0001). The myocardial infarction standardized mortality rate using the 2013 European standard (44.5 per 100,000) was significantly higher than the 1976 standard (27.6 per 100,000, p<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: