Key result
Adenosine unmasks catheter-induced mechanical block in the SVC during ablation.
Why the study?
Pharmacological agents including adenosine were previously reported unable to revive traumatized myocardial tissues such as catheter-induced mechanical blocks.
Case Report (n=1)
This case suggests that adenosine may be clinically useful for unmasking bumped sites (catheter-induced mechanical blocks) during radiofrequency ablation.
Adenosine may unmask catheter-induced mechanical blocks during SVC ablation; hypothesis-generating case report requiring prospective validation.
Adenosine can hyperpolarize the atrial action potential, which helps rapidly re-establish the membrane potential in ablated sites and unmask "dormant conduction." It has been reported that pharmacological agents, including adenosine, were unable to revive traumatized tissues. We present the first case of the catheter-induced mechanical block ("bump" phenomenon) that was unmasked with adenosine administration in the working myocardium of the superior vena cava. This result may be because, unlike before, we could determine the force of contact between the tip of the ablation catheter and the myocardial tissue. This case suggests the clinical usefulness of adenosine for unmasking bumped sites.
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Tsukahara et al. (2021) conducted a case report in Catheter-induced mechanical block during radiofrequency ablation (n=1). Adenosine was evaluated on Unmasking of catheter-induced mechanical block ('bump' phenomenon). Adenosine administration successfully unmasked a catheter-induced mechanical block ('bump' phenomenon) in the working myocardium of the superior vena cava during radiofrequency ablation.
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