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-consistency; (iv) introduce a sensitivity-analysis framework yielding closed-form bias bounds, E-values, and tipping points; and (v) characterise the sensitivity of the delivered estimand to the pre-specified borrowing rule via Fréchet differentiability. Simulations across 12 factorial scenarios confirm up to 49% RMSE reduction under compatibility, show that the estimators remain unbiased for the borrowing-dependent estimand when compatibility fails, and validate the sensitivity bounds. A worked example in metastatic colorectal cancer illustrates the complete analytical workflow.
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Bhattacharjee et al. (2026) studied this question.
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