Key result
Higher coronary jeopardy scores link to worse prognosis, dropping 5-year survival by ~41 percentage points.
Why the study?
The prognostic value of a coronary artery jeopardy score in nonsurgically treated patients with significant coronary artery disease was evaluated to improve risk stratification beyond the number of diseased vessels.
Does the coronary artery jeopardy score provide better prognostic information than the number of diseased vessels in nonsurgically treated patients with significant coronary artery disease?
Observational (n=462)
Does the coronary artery jeopardy score provide better prognostic information than the number of diseased vessels in nonsurgically treated patients with significant coronary artery disease?
The coronary artery jeopardy score provides superior prognostic stratification compared to simply counting the number of diseased vessels in nonsurgically treated CAD patients.
The prognostic value of a coronary artery jeopardy score was evaluated in 462 consecutive nonsurgically treated patients with significant coronary artery disease, but without significant left main coronary stenosis. The jeopardy score is a simple method for estimating the amount of myocardium at risk on the basis of the particular location of coronary artery stenoses. In patients with a previous myocardial infarction, higher jeopardy scores were associated with a lower left ventricular ejection fraction. When the jeopardy score and the number of diseased vessels were considered individually, each descriptor effectively stratified prognosis. Five year survival was 97% in patients with a jeopardy score of 2 and 95, 85, 78, 75 and 56%, respectively, for patients with a jeopardy score of 4, 6, 8, 10 and 12. In multivariable analysis when only jeopardy score and number of diseased vessels were considered, the jeopardy score contained all of the prognostic information. Thus, the number of diseased vessels added no prognostic information to the jeopardy score. The left ventricular ejection fraction was more closely related to prognosis than was the jeopardy score. When other anatomic factors were examined, the degree of stenosis of each vessel, particularly the left anterior descending coronary artery, was found to add prognostic information to the jeopardy score. Thus, the jeopardy score is a simple method for describing the coronary anatomy. It provides more prognostic information than the number of diseased coronary arteries, but it can be improved by including the degree of stenosis of each vessel and giving additional weight to disease of the left anterior descending coronary artery.(ABSTRACT TRUNCATED AT 250 WORDS)
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Califf et al. (1985) conducted an observational in Significant coronary artery disease (n=462). Coronary artery jeopardy score was evaluated on Five year survival. Higher coronary artery jeopardy scores stratified prognosis, with 5-year survival decreasing from 97% for a score of 2 down to 56% for a score of 12.
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