Key result
Beetroot powder reduces total cholesterol by ~10% in men with early-stage arterial hypertension.
Why the study?
The effects of beetroot powder on serum lipids and inflammatory and metabolic markers in patients with early-stage arterial hypertension were not well evaluated.
Does beetroot powder supplementation improve serum lipid profiles and inflammatory markers in men with early-stage arterial hypertension?
Does beetroot powder supplementation improve serum lipid profiles and inflammatory markers in men with early-stage arterial hypertension?
A 7-day course of beetroot powder supplementation was associated with modest reductions in total cholesterol, aminotransferases, and inflammatory markers in a small cohort of men with early-stage arterial hypertension.
Beetroot powder may improve lipids and liver enzymes in early hypertension; hypothesis-generating and requires randomized confirmation before practice change.
Aim — Beetroot is a natural source of nitrate and nitrite ions and is known to provide various benefits in healthy volunteers. The present pilot clinical study was aimed to evaluate the effects of beetroot powder (BETA-NO●-BOOST) on serum lipids and inflammatory and metabolic markers in patients with early-stage arterial hypertension to assess feasibility of a subsequent expanded randomized crossover-controlled trial. Materials and Methods — The present study enrolled 22 male patients with early-stage AH treated for 7 days with an oral daily dose of 20 g BETA-NO●-BOOST equivalent to 650-700 mg of nitrate and nitrite ions (NOx). Blood samples were collected at baseline and at endpoint and used to assay serum levels of lipids and inflammatory and metabolic markers. Results — Total levels of cholesterol and alanine aminotransferase were decreased by 10% and 18.5% (p<0.05), respectively, in all patients after 7-day use of beetroot powder. Hemoglobin concentration was decreased by 3.2% in 71% of the participants (p=0.001). The levels of C-reactive protein were decreased by 1.7-fold and leukocyte counts were decreased by 1.2x10⁹/L in 57% and 62% of the participants, respectively (p<0.05). Levels of blood glucose, creatinine, aspartate aminotransferase, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and platelets were decreased in more than 50% of the participants. Conclusion — The results support feasibility of an expanded randomized crossover controlled study of BETA-NO●-BOOST, suggesting that consumption of dietary nitrate from natural plant sources may be associated with nitric oxide production to account for potential beneficial use of BETA-NO●-BOOST in various inflammatory and cardiovascular diseases.
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Samatova et al. (2025) studied Early-stage arterial hypertension (n=22). Beetroot powder (BETA-NO●-BOOST) vs. Baseline was evaluated on Total cholesterol (10% decrease, p=<0.05). Consumption of beetroot powder for 7 days reduced total cholesterol by 10% and alanine aminotransferase by 18.5% in male patients with early-stage arterial hypertension.
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