Key result
Complete surgical resection achieves uneventful 1-year follow-up in intravenous leiomyomatosis.
Why the study?
Intravenous leiomyomatosis is rare but can have devastating consequences when extending into cardiac chambers, requiring awareness in differential diagnosis of venous thrombosis in reproductive or premenopausal women.
Case Report (n=1)
Intravenous leiomyomatosis should be considered in the differential diagnosis of venous thrombosis in reproductive or premenopausal women, as it can extend into cardiac chambers and have devastating consequences.
Supports diagnostic vigilance for intravascular leiomyomatosis in premenopausal women with venous thrombosis; leaves open optimal management protocols.
Intravenous leiomyomatosis is characterized by the growth of leiomyomatous tissue within the venous walls. It is rare but can have devastating consequences when extending into cardiac chambers. A 45-year woman presented with abdominal pain and thrombosis of left ovarian vein extending to the renal vein. Intravenous leiomyomatosis was suspected on imaging, due to the association with uterine myomas. Left nephrectomy with complete hysterectomy, right salpingectomy and left adnexectomy were performed. Follow-up at one-year was uneventful. Even rare, vascular surgeons should include intravenous leiomyomatosis in their differential diagnosis of venous thrombosis in a reproductive or premenopausal woman regardless of symptoms.
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Treil et al. (2026) conducted a case report in Intravenous leiomyomatosis (n=1). Left nephrectomy with complete hysterectomy, right salpingectomy and left adnexectomy was evaluated on Clinical outcome at one year. Surgical resection consisting of left nephrectomy, complete hysterectomy, right salpingectomy, and left adnexectomy resulted in an uneventful one-year follow-up in a patient with intravenous leiomyomatosis.
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