Key result
PASCAL Ace TEER achieves safe, effective mitral repair despite heavy calcification and prior TAVR.
Why the study?
Mitral transcatheter edge-to-edge repair in patients with prior TAVR and severe mitral annular calcification poses procedural challenges that require clarification.
Case Report (n=1)
M-TEER can be feasible and safe in complex anatomies such as prior TAVR and severe mitral annular calcification when using careful preprocedural planning and intraprocedural imaging.
Mitral transcatheter edge-to-edge repair (M-TEER) in the setting of prior transcatheter aortic valve replacement (TAVR) and severe mitral annular calcification (MAC) can pose procedural challenges. We describe the case of an 82-year-old woman with prior TAVR (29 mm EVOLUT FX+; Medtronic), P2 flail, and heavy circumferential MAC underwent M-TEER with the PASCAL Ace device (Edwards Lifesciences). This case illustrates that M-TEER can be performed safely and effectively in anatomies complicated by severe MAC and prior TAVR with careful preprocedural planning, intraprocedural imaging, and operator experience.
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Saad et al. (2026) conducted a case report in Severe mitral annular calcification, prior transcatheter aortic valve replacement, and P2 flail (n=1). Mitral transcatheter edge-to-edge repair (M-TEER) with PASCAL Ace device was evaluated. Mitral transcatheter edge-to-edge repair using the PASCAL Ace device was safely and effectively performed in a patient with heavy circumferential mitral annular calcification and prior TAVR.
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