Study of Electrocardiography and Echocardiography changes in patients of acute cerebrovascular accidents presenting to the Emergency Department

Q: What are the key findings of this study?

Acute cerebrovascular accidents were associated with a high prevalence of cardiac abnormalities, with 94.0% of patients exhibiting abnormal ECG findings and 89.6% showing abnormal echocardiography results.

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Acute Cerebrovascular Accident (CVA) (n=67). Intervention: Acute cerebrovascular accident (CVA). Primary outcome: Prevalence of abnormal electrocardiographic (ECG) findings.

Q: What does this research mean for the field?

Acute cerebrovascular accidents are associated with a high prevalence of cardiac dysfunction, with 94.0% of emergency department patients showing abnormal ECG findings and 89.6% demonstrating abnormal echocardiographic results. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

Mavudelli Sharmila Jayaram; Soumya Chandrashekar; Radhika Wanjale; Sumat Dadkar; Shrikanth Muralidharan; SS Gill Gill

doi:10.55218/jasr.2026170608

July 3, 2026Journal of Advanced Scientific ResearchOpen Access

Study of Electrocardiography and Echocardiography changes in patients of acute cerebrovascular accidents presenting to the Emergency Department

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Key result

Acute stroke is linked to abnormal ECG findings in ~94% of patients presenting acutely.

n=67

Why the study?

There is limited data on electrocardiographic and echocardiographic cardiac assessments in acute cerebrovascular accident patients presenting to emergency wards in Indian hospitals.

Key Points

To evaluate the prevalence and patterns of electrocardiographic and echocardiographic abnormalities in patients presenting with acute cerebrovascular accidents to an emergency department.
Prospective observational study conducted in an emergency department of a tertiary care center in urban India, enrolling 67 adult patients (mean age 57.87±15.22 years) with acute stroke.
All patients underwent 12-lead electrocardiography (ECG) and 2D echocardiography to identify cardiac presentations across stroke subtypes (53.7% ischemic, 41.8% hemorrhagic, and 4.5% other).
Associations between stroke subtypes and cardiac findings were evaluated using Chi-square and Fisher's exact tests with statistical significance defined as p<0.05.
Abnormal ECG findings occurred in 94.0% of patients (63/67), with rates differing significantly across stroke types: 91.7% in ischemic stroke, 100.0% in hemorrhagic stroke, and 66.7% in other strokes (p=0.046).
Abnormal echocardiographic findings were present in 89.6% of patients overall (60/67), including 86.1% of ischemic stroke cases, 92.9% of hemorrhagic stroke cases, and 100.0% of other stroke cases (p=0.568).
Left ventricular dysfunction was the predominant echocardiographic abnormality, identified in 80.6% of ischemic stroke cases, 82.1% of hemorrhagic stroke cases, and 100.0% of other stroke cases (p=0.700).

Study Design

Type

Observational (n=67)

Multicenter

No

Structured PICO

P

Population

67 adult patients with acute cerebrovascular accidents presenting within 72 hours of symptom onset underwent prospective evaluation for electrocardiographic and echocardiographic abnormalities.

O

Outcome

Patterns of changes in electrocardiography (ECG) and echocardiography (Echo) studies upon emergency department presentationsurrogate

A very high prevalence of ECG and echocardiographic abnormalities accompanies acute cerebrovascular accidents upon presentation, underscoring the clinical importance of routine, early cardiac evaluation in this population.

Limitations

Small sample size
Lesion heterogeneity (size, location)
Observational design cannot establish absolute causality between the cerebrovascular event and cardiac abnormalities
Advanced echocardiographic techniques and quantitative strain analysis were not performed due to emergency department workflow constraints
Lack of longitudinal cardiac follow-up and prior cardiac status documentation
Observational descriptive design cannot establish absolute causality between the stroke and cardiac abnormalities
Lack of prior cardiac status documentation
Advanced echocardiographic techniques and quantitative strain analysis were not performed due to emergency department constraints

Implication

High cardiac abnormality rates in acute stroke support early evaluation; leaves open whether screening improves outcomes in prospective studies.

Abstract

Cardiac abnormalities commonly accompany Acute Cerebrovascular accidents (CVA). This heart-brain interaction is reflected in the echocardiography and electrocardiographic changes. There is limited data on the assessments in the emergency ward of Indian hospitals. This study aims to evaluate the patterns of cardiac presentations among cases of CVA. The study was prospective observational in nature. The sample size was 67. All cases were above 18 years of age. All cases with any form of stroke underwent 12 lead ECG and an echo. Chi-square/Fisher’s exact test analysed the associations between stroke type and the cardiac findings. All p-values <0.05 were considered to be statistically significant. The mean age of cases was 57.9 years. More males were affected, and cases of ischemic stroke were higher (53.7%). Abnormality with cardiac findings was seen with 94% cases. Left ventricular dysfunction was predominant. Across the stroke subtypes, cardiac findings did not differ statistically. There is a higher prevalence of cardiac abnormalities among acute CVA cases. Routine cardiac evaluation should be carried out among patients before transferring them further to departments. Early treatment will help to prevent complications and reduce mortality rates.

Discussion

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Cite This Study

Jayaram et al. (2026) conducted an observational in Acute Cerebrovascular Accident (CVA) (n=67). Acute cerebrovascular accident (CVA) was evaluated on Prevalence of abnormal electrocardiographic (ECG) findings. Acute cerebrovascular accidents were associated with a high prevalence of cardiac abnormalities, with 94.0% of patients exhibiting abnormal ECG findings and 89.6% showing abnormal echocardiography results.

synapsesocial.com/papers/6ad0fc963afa093ea9acfef0 https://doi.org/10.55218/jasr.2026170608

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Study of Electrocardiography and Echocardiography changes in patients of acute cerebrovascular accidents presenting to the Emergency Department

Key Points

Study Design

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Study of Electrocardiography and Echocardiography changes in patients of acute cerebrovascular accidents presenting to the Emergency Department

Key Points

Study Design

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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