Key result
Malignant mitral valve glomus tumor triggers recurrent embolic events including NSTEMI and stroke.
Why the study?
Malignant glomus tumors involving cardiac structures are extremely rare and can cause embolic events, requiring multidisciplinary diagnosis and management.
Case Report (n=1)
Intracardiac malignant glomus tumors are extremely rare but can present with recurrent embolic events requiring prompt multidisciplinary evaluation and surgical resection.
Multidisciplinary evaluation remains essential for cardiac tumors with emboli; this third case extends the two prior reports of intracardiac malignant glomus tumors.
CASE SUMMARY: We report a case of a malignant glomus tumor involving the mitral valve, resulting in repeat presentations with arterial embolic events including non-ST-segment elevation myocardial infarction and stroke. This is the third existing case report of an intracardiac malignant glomus tumor and highlights the need for a multidisciplinary approach to the diagnosis and management of cardiac tumors. TAKE-HOME MESSAGES: Glomus tumors are extremely rare, and even less commonly malignant. They can involve cardiac structures and pose risk for embolic events. Patients with cardiac glomus tumors should be evaluated rapidly by a multidisciplinary cardio-oncology team and receive prompt referral for consideration of surgical resection.
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Franquiz et al. (2026) conducted a case report in Malignant glomus tumor involving the mitral valve (n=1). Malignant glomus tumor of the mitral valve was evaluated on Arterial embolic events including NSTEMI and stroke. A rare malignant glomus tumor involving the mitral valve resulted in repeat presentations with arterial embolic events including non-ST-segment elevation myocardial infarction and stroke.
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