Key result
VA-ECMO without systemic anticoagulation successfully bridges peripartum cardiogenic shock to delivery and maternal cardiac recovery.
Why the study?
Preeclampsia with severe features complicated by acute cardiopulmonary failure is rare and may require maternal stabilization before delivery.
Case Report (n=1)
Venoarterial extracorporeal membrane oxygenation can be successfully utilized without systemic anticoagulation as an emergency bridge to cesarean delivery in critically unstable pregnant patients with severe preeclampsia and acute cardiopulmonary failure.
Preeclampsia with severe features complicated by acute cardiopulmonary failure is rare and may require maternal stabilization before delivery. A 37-year-old woman at 36 weeks' gestation with gestational hypertension presented with sudden dyspnea, severe hypertension, profound hypoxemia, and rapid loss of consciousness. Echocardiography showed severe left ventricular dysfunction with an ejection fraction below 20%, with increasing vasopressor requirements despite intubation and mechanical ventilation. Because cesarean delivery before cardiopulmonary support was considered unsafe, venoarterial extracorporeal membrane oxygenation was initiated as a bridge to delivery without systemic anticoagulation. Cesarean delivery commenced concurrently with target extracorporeal membrane oxygenation flow. Maternal cardiac function recovered over 48 h; mechanical support was discontinued on day 3, and she left intensive care on day 9. The neonate required intubation and therapeutic hypothermia but was discharged home in good condition. This case supports individualized delivery timing and venoarterial extracorporeal membrane oxygenation as rescue support in selected critically unstable patients.
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Vajter et al. (2026) conducted a case report in Preeclampsia with severe features complicated by acute cardiopulmonary failure (n=1). Venoarterial extracorporeal membrane oxygenation (VA-ECMO) was evaluated. Venoarterial extracorporeal membrane oxygenation successfully served as a bridge to cesarean delivery without systemic anticoagulation, allowing maternal cardiac recovery over 48 hours.
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