Key result
Stopping inotropes and adding fluids, vasopressors, and beta-blockers successfully reverses post-TAVR suicidal left ventricle.
Why the study?
The suicidal left ventricle is a rare but potentially fatal complication after TAVR caused by dynamic LV outflow tract obstruction following abrupt afterload reduction, requiring distinct management from conventional cardiogenic shock.
Case Report (n=1)
This case highlights the critical importance of early echocardiographic diagnosis of 'suicidal left ventricle' post-TAVR, as its treatment requires avoiding inotropes and utilizing volume expansion, vasopressors, and beta-blockers.
May guide physiology-directed stabilization of suicidal LV shock post-TAVR; leaves open prospective validation before wider adoption.
BACKGROUND: The "suicidal left ventricle" (LV) is a rare but potentially fatal complication after transcatheter aortic valve replacement (TAVR), caused by dynamic LV outflow tract obstruction following abrupt afterload reduction. CASE SUMMARY: A 77-year-old woman with severe symptomatic aortic stenosis underwent successful TAVR. Shortly after the procedure, she developed hypotension, hypoperfusion, and cardiogenic shock. Initial management with fluids and vasopressors provided transient improvement; however, inotropic support worsened her condition. Urgent transthoracic echocardiography revealed a small, hyperdynamic LV with a dagger-shaped dynamic intraventricular gradient, without prosthetic dysfunction. A diagnosis of suicidal LV was established. Inotropes were discontinued, and treatment with volume expansion, vasopressors, and beta-blockers led to rapid hemodynamic recovery. DISCUSSION: This case highlights the importance of early recognition of dynamic obstruction after TAVR and the need for targeted hemodynamic management, which differs from the conventional cardiogenic shock treatment. TAKE-HOME MESSAGE: Early echocardiographic diagnosis and avoidance of inotropes are critical to reverse this potentially reversible cause of cardiogenic shock after TAVR.
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Ossa et al. (2026) conducted a case report in Severe symptomatic aortic stenosis and post-TAVR cardiogenic shock (n=1). Targeted hemodynamic management (volume expansion, vasopressors, beta-blockers) vs. Inotropic support (initial therapy) was evaluated. Cardiogenic shock due to a suicidal left ventricle after TAVR was successfully reversed by discontinuing inotropes and initiating volume expansion, vasopressors, and beta-blockers.
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