Key result
Increasing frailty is an important metric that has been independently associated with increased mortality after both transcatheter aortic and mitral valve replacements.
Frailty indices are increasingly recognized as valuable tools to better stratify risk and predict mortality in patients undergoing surgical and transcatheter valve replacements.
Over recent decades, there has been increasing emphasis on the use of validated frailty indices to better stratify surgical risk in cardiac surgery.1-2 Frail patients have been shown to have worse outcomes in the surgical valve replacement literature, and with the emergence of transcatheter therapies, frailty metrics have proven valuable tools beyond traditional risk assessment models for heart valve teams to use in their comprehensive evaluation of patients. A previous analysis of the Centers for Medicare & Medicaid Services (CMS) Medicare Provider and Review (MedPAR) database demonstrated that increasing frailty was independently associated with increased mortality after both transcatheter aortic and mitral valve replacements.
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Liu et al. (2026) conducted an editorial in Cardiac surgery and transcatheter valve replacements. Frailty was evaluated. Increasing frailty is an important metric that has been independently associated with increased mortality after both transcatheter aortic and mitral valve replacements.
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