Key result
Stellate ganglion block transiently suppresses refractory VT as a bridge to surgical sympathetic denervation.
Why the study?
Some patients with electrical storm remain refractory to conventional antiarrhythmic therapy and catheter ablation, necessitating alternative treatment approaches such as autonomic modulation.
Does stepwise autonomic modulation with stellate ganglion block followed by cardiac sympathetic denervation suppress drug-refractory electrical storm in a patient with ischemic cardiomyopathy?
Case Report (n=1)
No
Does stepwise autonomic modulation with stellate ganglion block followed by cardiac sympathetic denervation suppress drug-refractory electrical storm in a patient with ischemic cardiomyopathy?
This case highlights that stellate ganglion block is an effective minimally invasive intervention for immediate, transient suppression of refractory electrical storm, serving as a vital bridge to definitive surgical cardiac sympathetic denervation.
Answers are grounded in this paper and cite their sources.
May support stellate ganglion block as bridge in refractory VT; leaves open need for prospective trials before wider adoption.
Electrical storm (ES) is a critical cardiac emergency characterized by recurrent, life-threatening ventricular arrhythmias occurring within a short period, most commonly in patients with structural heart disease, particularly those who have an implantable cardioverter-defibrillator (ICD) for secondary prevention, as the device records recurrent ventricular arrhythmias that characterize electrical storm. Despite advances in antiarrhythmic therapy and catheter ablation, some patients remain refractory to conventional management, resulting in significant morbidity and mortality. Recent evidence highlights the potential role of autonomic modulation, particularly stellate ganglion block (SGB), as an adjunctive or rescue therapy in these cases. This article presents the clinical case of a 75-year-old patient with ischemic cardiomyopathy and recurrent episodes of sustained ventricular tachycardia refractory to standard pharmacologic therapy (amiodarone, lidocaine, beta-blockers) and ICD interventions. This case emphasizes the importance of recognizing SGB as a viable, minimally invasive, and potentially life-saving intervention for patients with ES who do not respond to conventional treatment. Furthermore, as its effects are transient, SGB may serve as a diagnostic and bridging step toward definitive sympathetic modulation through surgical cardiac sympathetic denervation in recurrent or refractory cases.
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Galkuvienė et al. (2026) conducted a case report in Refractory ventricular tachycardia (Electrical storm) (n=1). Stellate ganglion block followed by cardiac sympathetic denervation was evaluated. Stellate ganglion block provided immediate but transient suppression of refractory ventricular tachycardia, serving as an effective bridge to definitive surgical cardiac sympathetic denervation.
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