Key result
Misinterpreting MI symptoms is linked to ~6.2-fold higher odds of pre-hospital delay over 2 hours.
Why the study?
Understanding determinants contributing to pre-hospital delay in myocardial infarction is essential to improve early treatment and reduce mortality.
What are the patient-level predictors of pre-hospital delay >2 hours in adults with myocardial infarction?
Cross-Sectional (n=105)
No
What are the patient-level predictors of pre-hospital delay >2 hours in adults with myocardial infarction?
Identifying modifiable factors such as symptom misinterpretation underscores the need for targeted awareness campaigns to minimize pre-hospital delays and improve myocardial infarction outcomes.
Answers are grounded in this paper and cite their sources.
Symptom misinterpretation was associated with pre-hospital MI delay; hypothesis-generating for education interventions to improve timely presentation.
Background: Myocardial infarction (MI) is a leading cause of death globally, with early treatment being critical in reducing mortality. Understanding determinants contributing to pre-hospital delay is essential to improve the outcome. Objective: The present study evaluated the time distribution between symptom onsets to hospital arrival and associated factors among patients with MI. Materials and Methods: A cross-sectional study included 105 MI patients admitted to a tertiary care teaching hospital in Ahmedabad city during March to August 2024. Patients fulfilling the inclusion criteria were interviewed using a pre-tested, semi-structured questionnaire. Pre-hospital delay was considered as the time elapsed from symptom onset to arrival at a tertiary care hospital among MI patients. Delay was categorized into two groups: ≤2 hours and >2 hours. Appropriate statistical tests were used to assess the association between factors influencing the time from symptom onset to hospital arrival. Results: The median time from symptom onset to tertiary hospital arrival was 90 minutes (Interquartile range: 45–210 minutes). Out of a total of 105 participants, 37 (35.2%) experienced delays of >2 hours. Younger age (odds ratio [OR]: 2.16; P = 0.171), female gender (OR: 3.2; P = 0.03), and nuclear family structure (OR: 1.56; P = 0.39) were predictors of pre-hospital delay. Patients having previous similar episodes of symptoms or who misinterpreted them as non-heart-related also reported longer delays. Conclusion: Approximately one-third of patients reported a delay of >2 hours. Younger age, female gender, nuclear family structure, previous episodes of symptoms, and misinterpretation of symptoms were significant determinants of pre-hospital delay in MI patients.
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Shah et al. (2026) conducted a cross-sectional in Myocardial Infarction (n=105). Symptom misinterpretation (as non-heart-related) vs. Correct interpretation of symptoms as a heart attack was evaluated on Pre-hospital delay > 2 hours (OR 6.19, 95% CI 1.8-21.2, p=0.004). Patients who misinterpreted their myocardial infarction symptoms as non-heart-related had a significantly higher likelihood of experiencing a pre-hospital delay of >2 hours (OR 6.19).
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