Key result
Lowest dietary fiber intake linked to ~3-fold higher all-cause and cancer mortality in men.
Why the study?
The relationship between dietary fibre intake and long-term mortality from coronary heart disease, cancer, and all causes was investigated to clarify potential protective effects.
Does higher dietary fiber intake reduce 10-year mortality from coronary heart disease, cancer, and all causes in middle-aged men?
Cohort (n=871)
No
Does higher dietary fiber intake reduce 10-year mortality from coronary heart disease, cancer, and all causes in middle-aged men?
A diet high in dietary fiber (≥37 g/day) is independently associated with lower 10-year all-cause and cancer mortality in middle-aged men, though its isolated protective effect against CHD mortality was not maintained after multivariate adjustment.
In 1960, 871 middle-aged men in the town of Zutphen, The Netherlands, participated in a survey of risk indicators (including diet) for coronary heart disease (CHD). Information was collected about the usual food intake for the 6--12 months before the interview by the cross-check dietary history method. During 10 years of follow-up, 107 men died from all causes, 37 from CHD, and 44 from cancer. Mortality from CHD was about four times higher for men in the lowest quintile of dietary-fibre intake than for those in the highest quintile, but this inverse relation disappeared after multivariate analyses. Rates of death from cancer and from all causes were about three times higher for men in the lowest quintile of dietary-fibre intake than for those in the highest quintile, and these relations persisted after multivariate analyses. A diet containing at least 37 g dietary fibre per day may be protective against chronic diseases in Western societies.
No takes yet. Share an insight, caveat, or question.
Kromhout et al. (1982) conducted a cohort in coronary heart disease (n=871). Dietary-fibre intake vs. Highest quintile of dietary-fibre intake was evaluated on 10-year mortality from coronary heart disease, cancer, and all causes. Men in the lowest quintile of dietary-fibre intake had about three times higher rates of death from cancer and all causes than those in the highest quintile over 10 years of follow-up.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: