Key result
Myocardial perfusion imaging effectively evaluates myocardial ischemia and viability in pediatric heart diseases.
Why the study?
The diagnostic and prognostic role of myocardial perfusion imaging in pediatric cardiology requires clarification including radiopharmaceuticals, stress protocols, and perfusion patterns in congenital and acquired heart diseases.
Supports MPI for pediatric ischemia evaluation; leaves open need for outcome trials before routine adoption.
Diagnostic and prognostic power of myocardial perfusion imaging in patients with coronary artery disease has been demonstrated with planar imaging which was further improvised with addition of gated SPECT and newer Technetium labeled myocardial perfusion tracers like SestaMIBI, Tetrofosmin. Myocardial perfusion abnormalities at rest and after stress are considered to be the best predictors of cardiac event-free survival in adults with ischemic heart disease. This article highlights various myocardial perfusion imaging (MPI) radiopharmaceuticals, exercise procedures, pharmacological stress protocols, indications for MPI and myocardial perfusion patterns in children with some of the common congenital and acquired heart diseases.
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Padma Subramanyam (2009) conducted a review in Pediatric cardiovascular diseases. Myocardial perfusion imaging (MPI) was evaluated. Myocardial perfusion imaging is a valuable physiological modality for evaluating myocardial ischemia and viability in children with congenital and acquired heart diseases.
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