Key result
Oral amiodarone prevented clinical recurrences over 1 year of follow-up in a Southeast Asian man with sudden cardiac death syndrome, even though polymorphic ventricular tachycardia remained inducible.
Why the study?
The syndrome of sudden cardiac death in Southeast Asians has only recently been recognized and described in the American medical literature.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
Amiodarone may suppress recurrences in sudden cardiac death syndrome despite inducible VT; leaves open its role pending prospective data.
The syndrome of sudden cardiac death in southeast Asians has only recently been given attention in the American medical literature. This case report describes a patient who presented with this rare syndrome. The physical examination, Holter monitor, 2-D echocardiogram, exercise treadmill test, radionuclide ventriculogram, coronary angiography, and endomyocardial biopsy were all normal. Programmed ventricular stimulation reproducibly induced sustained polymorphic ventricular tachycardia. Oral procainamide, oral quinidine and oral quinidine plus propranolol were not successful in suppressing inducible polymorphic ventricular tachycardia. The arrhythmia remained inducible after six weeks of oral amiodarone therapy. However, he has no clinical recurrences while on amiodarone after one year of follow-up.
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GILBERT et al. (1986) conducted a case report in Sudden cardiac death syndrome (n=1). Oral amiodarone was evaluated on Clinical recurrences of polymorphic ventricular tachycardia. Oral amiodarone prevented clinical recurrences over 1 year of follow-up in a Southeast Asian man with sudden cardiac death syndrome, even though polymorphic ventricular tachycardia remained inducible.
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