Key result
Pulmonary venous flow reversal, but not systolic flow blunting, is linked to severe MR in AF.
Why the study?
The correlation between mitral valve regurgitant severity and pulmonary venous systolic flow decrease/reversal in patients with atrial fibrillation was not established.
Observational (n=66)
Pulmonary venous flow reversal may aid severe MR detection in AF; leaves open incremental diagnostic value and needs prospective validation.
Studies have shown that pulmonary systolic velocities are decreased in patients with atrial fibrillation, but none have shown the correlation between mitral valve regurgitant severity and the amount of systolic flow decrease/reversal in these patients. In patients with normal sinus rhythm, a finding of decreased systolic flow <0.4 m/s is consistent with moderate mitral regurgitation, and systolic flow reversal is consistent with severe mitral regurgitation. Doppler recordings of 66 patients who were in atrial fibrillation at the time of their transthoracic echocardiograms (January-July 1995, January 1996-February 1997) were analyzed to show the statistical relation between mitral regurgitant severity and the amount of systolic flow decrease/reversal. This study showed that a decrease in systolic flow velocities expected in patients with atrial fibrillation and the amount of decrease does not correlate statistically with the severity of mitral regurgitant lesions. In addition, flow reversal in the pulmonary veins is not expected in patients with atrial fibrillation, and such a finding is strongly associated with severe mitral regurgitant lesions.
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Elijah et al. (1998) conducted an observational in Atrial Fibrillation and Mitral Regurgitation (n=66). Pulmonary venous flow patterns (systolic flow decrease or reversal) was evaluated on Correlation between mitral regurgitant severity and the amount of systolic flow decrease or reversal. Pulmonary venous flow reversal was strongly associated with severe mitral regurgitation in patients with atrial fibrillation, whereas the degree of systolic flow decrease did not correlate.
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