Key result
Severe tricuspid and pulmonic valve dysplasia reveals diffuse myxomatous changes in a canine model.
Why the study?
Histological characteristics of tricuspid valve dysplasia and pulmonic stenosis in young dogs are not well described.
Case Report (n=1)
This report documents the first canine case of an ontogenetic manifestation of myxomatous tissue concurrently affecting both the tricuspid and pulmonary valves.
Answers are grounded in this paper and cite their sources.
Rare congenital tricuspid-pulmonic dysplasia described in a puppy; leaves open ontogenetic mechanisms of myxomatous valve anomalies.
A six-week-old Labrador retriever was presented for lethargy and anorexia, revealing a systolic heart murmur. Tricuspid valve dysplasia involving the whole tricuspid valve apparatus and the right ventricular wall was found, and an additional pulmonic stenosis was present. Histopathological examination of the tricuspid and pulmonary leaflets highlighted an unusual myxomatous mesenchymal component, interpreted as being of ontogenetic origin.
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Schoebel et al. (2025) conducted a case report in Pulmonic stenosis and tricuspid valve dysplasia (n=1). Histopathological examination of a six-week-old Labrador puppy with severe tricuspid and pulmonic valve dysplasia revealed a unique ontogenetic manifestation of diffuse myxomatous tissue in both valves.
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