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Rubiginones and piperafizines were isolated from the fermentation broths of Streptomyces griseorubiginosus Q144-21} and Streptoverticillium aspergilloides Q576-22), respectively, in our screening program for potentiators of vincristine (VCR)induced cytotoxicity against human colorectal carcinoma Moser cells in vitro.Among their
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Ogasawara et al. (1992) studied this question.
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