Key result
Standard heart failure medical therapy restores left ventricular function in atypical apical-sparing Takotsubo cardiomyopathy.
Why the study?
Takotsubo Cardiomyopathy can rarely present atypically with apical wall sparing, complicating diagnosis and management.
Case Report (n=1)
Highlights potential LV recovery with HF therapy in apical-sparing Takotsubo; leaves open need for prospective data on rare variants.
BACKGROUND: Takotsubo Cardiomyopathy (TTC) is an uncommon cause of acute reversible ventricular systolic dysfunction in the absence of obstructive Coronary Artery Disease (CAD). Typically manifesting as apical wall ballooning, TTC can rarely present atypically with apical wall sparing. CASE REPORT: A 62-year-old female presented with complaints of chest pain and features mimicking acute coronary syndrome. Coronary angiogram revealed no obstructive CAD and left ventriculogram showed reduced ejection fraction, normal left ventricular apex and hypokinetic mid-ventricles consistent with atypical TTC. The patient was discharged home on heart failure medications and a follow-up transthoracic echocardiogram demonstrated improved left ventricular function with no wall motion abnormality. CONCLUSION: This case report provides an insight into the diagnosis and management of TTC in the absence of pathognomic features.
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Ludhwani et al. (2019) conducted a case report in Atypical Takotsubo Cardiomyopathy (n=1). Heart failure medications (supportive care) was evaluated on Recovery of left ventricular function. A 62-year-old female with atypical Takotsubo cardiomyopathy characterized by apical wall sparing successfully recovered left ventricular function after being treated with heart failure medications.
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