Key result
In a forensic autopsy series of sudden deaths due to acute aortic wall failure, medial degeneration was the most frequent structural substrate, while mild inflammatory infiltration was present in 19.2% of cases.
Highlights that acute aortic rupture frequently occurs at diameters below traditional aneurysm thresholds (average 42 mm) and is primarily driven by structural weaknesses like medial degeneration and inflammation rather than just atherosclerosis or hypertension.
Dear Editor,With great interest, I read the article by Beşkoç al. [1] titled "Sudden deaths due to acute aortic wall failure: A 10-year forensic autopsy series" published in Turkish Journal of Thoracic and Cardiovascular Surgery.I wouldlike to highlight the importance of this issue in cardiovascular surgery.
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İhsan Alur (2026) conducted a letter in Acute aortic wall failure (n=78). Medial degeneration and inflammation was evaluated on Histopathological prevalence of medial degeneration and inflammatory infiltration. In a forensic autopsy series of sudden deaths due to acute aortic wall failure, medial degeneration was the most frequent structural substrate, while mild inflammatory infiltration was present in 19.2% of cases.
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