Key result
Long-term anticoagulation is recommended for LV mural thrombus or cardiomyopathy when bleeding risk allows.
Why the study?
The identification and management of left ventricular mural thrombus in patients with myocardial infarction and cardiomyopathy require careful consideration of anticoagulation therapy balanced against risks.
May warrant anticoagulation for post-MI LV mural thrombus; leaves open confirmation by randomized trials.
• The identification of mural thrombus in patients with left ventricular aneurysm and mural thrombus probably warrants consideration of long-term anticoagulation. In patients with acute, large, anterior or anteroapical, transmural myocardial infarctions, serial noninvasive examinations are warranted to define a group of patients at high risk for the development of left ventricular aneurysm and/or mural thrombus. Anticoagulants should be considered in patients in whom mural thrombi develop as a complication of their infarction. Patients with congestive cardiomyopathy should be considered for long-term anticoagulation. These recommendations are all tempered by the realization that the use of anticoagulant therapy is not without its own risks. The decision to anticoagulate must be balanced against each individual patient's suitability for such therapy and the individual likelihood of the development of side effects. (Arch Intern Med1983;143:1567-1571)
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Nixon Jv (1983) conducted a review in Left ventricular mural thrombus, acute myocardial infarction, congestive cardiomyopathy. Anticoagulation was evaluated. Long-term anticoagulation is recommended for patients with left ventricular mural thrombus or congestive cardiomyopathy, though risks must be balanced against individual suitability.
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