Материнские, Акушерские И Перинатальные Исходы Беременности У Женщин С Некорригированными Септальными Врожденными Пороками Сердца

Q: What is the clinical evidence from this study?

Study design: Review. Population: Unrepaired atrial and ventricular septal defects during pregnancy. Intervention: Unrepaired atrial and ventricular septal defects vs. General pregnant population (implied). Primary outcome: Maternal cardiovascular, obstetric, and perinatal complications.

Q: What does this research mean for the field?

Pregnancy in women with unrepaired atrial and ventricular septal defects generally has favorable outcomes but carries an increased risk of preeclampsia, preterm birth, and cardiovascular complications depending on hemodynamic status. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Nigina Tojieva

doi:10.70413/ejar-v6-i9-57103

September 10, 2026Eurasian Journal of Academic ResearchOpen Access

Материнские, Акушерские И Перинатальные Исходы Беременности У Женщин С Некорригированными Септальными Врожденными Пороками Сердца

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Why the study?

The course of pregnancy and delivery outcomes in women with uncorrected atrial and ventricular septal defects require updated analysis to understand maternal, obstetric, and perinatal complications.

Key Points

To synthesize evidence on maternal, obstetric, and perinatal outcomes in pregnant women with unrepaired atrial and ventricular septal defects, identifying key risk factors and management strategies.
Conducted an analytical literature review of international and national cohort, population-based, and single-center studies, systematic reviews, and meta-analyses published primarily between 2020 and 2026.
Evaluated maternal cardiovascular complications, obstetric events, delivery modes, and perinatal outcomes, comparing atrial versus ventricular septal defects.
Assessed cardiovascular risk stratification instruments, including modified WHO (mWHO), CARPREG/CARPREG II, and ZAHARA criteria.
Maternal and perinatal outcomes are generally favorable in the absence of severe hemodynamic dysfunction, but risks escalate with impaired functional capacity, ventricular dysfunction, or pulmonary hypertension.
Cited nationwide data across 7,512 pregnancies in 4,015 women with congenital heart defects showed higher frequencies of heart failure, arrhythmias, cerebrovascular complications, cesarean delivery, and adverse neonatal events compared to unaffected peers.
Complication rates depend strongly on defect size, shunt hemodynamics, and coexisting factors like preeclampsia and fetal growth restriction rather than defect anatomy alone.

Structured PICO

P

Population

Pregnant women with unrepaired atrial and ventricular septal congenital heart defects.

O

Outcome

Maternal, obstetric, and perinatal complications, including cardiovascular events, preeclampsia, preterm birth, and adverse neonatal outcomes

Individualized risk stratification, multidisciplinary dynamic monitoring, and appropriate delivery planning are essential for safely managing pregnancies in women with unrepaired septal defects.

Limitations

Existing risk stratification models (mWHO, CARPREG, ZAHARA) do not provide universally accurate prediction of complications for all patient categories and individual combinations of factors.

Implication

Supports hemodynamic-guided monitoring in pregnancy; leaves open prospective validation of risk predictors.

Abstract

В статье представлен анализ современных данных о те-чении беременности и исходах родов у женщин с некор-ригированными дефектами межпредсердной и межже-лудочковой перегородок. Рассмотрены основные мате-ринские, акушерские и перинатальные осложнения, включая сердечно-сосудистые события, преэклампсию, преждевременные роды и неблагоприятные неонаталь-ные исходы. Показано, что риск осложнений определя-ется не только видом порока, но и его гемодинамиче-ской значимостью, функциональным состоянием сер-дечно-сосудистой системы и наличием сопутствующих факторов риска. Обоснована необходимость индивиду-альной оценки риска, динамического наблюдения и ра-ционального выбора тактики родоразрешения и ведения раннего послеродового периода.

Discussion

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Cite This Study

Nigina Tojieva (2026) conducted a review in Unrepaired atrial and ventricular septal defects during pregnancy. Unrepaired atrial and ventricular septal defects vs. General pregnant population (implied) was evaluated on Maternal cardiovascular, obstetric, and perinatal complications.

synapsesocial.com/papers/6ad49f5fcc23993462cc536a https://doi.org/10.70413/ejar-v6-i9-57103

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Материнские, Акушерские И Перинатальные Исходы Беременности У Женщин С Некорригированными Септальными Врожденными Пороками Сердца

Key Points

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Материнские, Акушерские И Перинатальные Исходы Беременности У Женщин С Некорригированными Септальными Врожденными Пороками Сердца

Key Points

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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