Chromosome-Based bla OXA-48 -Like Variants in Shewanella Species Isolates from Food-Producing Animals, Fish, and the Aquatic Environment

Carbapenems are considered last-resort antibiotics in health care. Increasing reports of carbapenemase-producing bacteria in food-producing animals and in the environment indicate the importance of this phenomenon in public health. Surveillance for carbapenemase genes and carbapenemase-producing bacteria in Dutch food-producing animals, environmental freshwater, and imported ornamental fish revealed several chromosome-based bla OXA-48 -like variants in Shewanella spp., including two new alleles, bla OXA-514 and bla OXA-515 . Carbapenemase genes were not associated with mobile genetic elements or Enterobacteriaceae .