Key result
Mechanical thrombectomy is linked to an absolute ~12% increase in blood pressure swings during early mobilization.
Why the study?
Factors associated with changes in blood pressure during early mobilization after mechanical thrombectomy for acute ischemic stroke were not well understood.
Observational (n=120)
No
Answers are grounded in this paper and cite their sources.
Warrants caution with early mobilization after mechanical thrombectomy; leaves open effects on outcomes and need for prospective protocols.
OBJECTIVE: To assess factors associated with changes in blood pressure during early mobilization protocol for patients with acute ischemic stroke who were treated with mechanical thrombectomy. DESIGN: Retrospective observational study. METHOD: We analyzed patients with acute ischemic stroke who were treated with mechanical thrombectomy (MT group, n=60) and patients who received conservative medical management (control group, n=60) matched by age and National Institute Health of Stroke Score at admission from April 2009 to July 2014. The proportion of patients with prominent blood pressure change during an early mobilization protocol was compared between the MT group and control group. Factors associated with prominent blood pressure change were also analyzed using multivariable logistic regression analysis. RESULT: The deviation in blood pressure response was much more significant in the MT than control group (13.3 vs. 1.7%, p<0.016). Logistic regression analysis showed the interval from admission to being able to sit in a wheelchair associated with prominent changes in blood pressure (odds ratio, 1.604; 95% confidence interval, 1.196-2.150; p<0.002). CONCLUSION: Our results showed that prominent changes in blood pressure during an early mobilization protocol can occur easily in patients with acute ischemic stroke after mechanical thrombectomy.
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Yagi et al. (2016) conducted an observational in Acute ischemic stroke (n=120). Mechanical thrombectomy vs. Conservative medical management was evaluated on Prominent blood pressure change during early mobilization protocol (p=0.016). Mechanical thrombectomy was associated with a significantly higher rate of prominent blood pressure changes during early mobilization compared to conservative medical management (13.3% vs 1.7%).
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