Key result
Intra-arterial nimodipine for post-subarachnoid hemorrhage vasospasm may cause basal ganglia vasogenic edema.
Why the study?
The intra-arterial administration of nimodipine is commonly used for cerebral vasospasm refractory to medical treatments, but complications such as vasogenic edema are not well characterized.
Case Report (n=2)
No
Answers are grounded in this paper and cite their sources.
Supports caution with intra-arterial nimodipine; leaves open incidence, mechanisms, and monitoring needs in larger cohorts.
The intra-arterial administration of nimodipine (IAN) is commonly used for cerebral vasospasm refractory to medical treatments. We report two cases of vasogenic edema after IAN. Our patients with aneurismal subarachnoid hemorrhage presented with vasospasm, which was treated by IAN. Consequently, vasogenic edema developed in the basal ganglia. Reperfusion following IAN for vasospasm may have the potential for inciting vasogenic edema in the ischemic brain.
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Ryu et al. (2011) conducted a case report in Aneurysmal subarachnoid hemorrhage with cerebral vasospasm (n=2). Intra-arterial nimodipine was evaluated on Development of vasogenic edema. Intra-arterial administration of nimodipine for cerebral vasospasm following subarachnoid hemorrhage may cause vasogenic cerebral edema in the basal ganglia.
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