Many theories on the pathogenesis of Zenker's diverticulum have been advanced, but not one of them is generally accepted. Recent reports describe structural histologic abnormalities in the cricopharyngeal muscle fibers, but the pathogenesis seems only a result of the individual anatomic structure in the pharyngoesophageal segment. Methods of treatment are diverticulectomy combined with extra-mucosal myotomy of the sphincter and endoscopic treatment. The latter is gaining in popularity as the operation of choice.
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Overbeek et al. (1994) studied this question.
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