Answers are grounded in this paper and cite their sources.
Mannosylated cationic vectors have been previously used for delivering DNA vaccines to antigen presenting cells (APCs) via mannose receptors expressed on the cell surface of APCs. Here we show that cationic amphiphiles containing mannose-mimicking quinic acid and shikimic acid headgroups deliver genes to APCs via mannose receptor. Cationic amphiphile with shikimic acid headgroup was more efficacious than its mannosyl counterpart in combating mouse tumor growth by dendritic cell (the most professional APC) based genetic immunization.
No takes yet. Share an insight, caveat, or question.
Ramishetti et al. (2010) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: