Key result
Surgery for active infective endocarditis is linked to ~10% in-hospital mortality and favorable midterm survival.
Why the study?
Survival and recurrence rates after surgical treatment in patients with active infective endocarditis were not well characterized.
Cohort (n=80)
No
Answers are grounded in this paper and cite their sources.
Surgery for active IE yields >90% 18-month survival post-discharge with low recurrence; leaves open need for prospective trials before practice change.
Background. Aim of present investigation was to analyze survival and recurrence rate in patients with active endocarditis referred to our centre for surgical treatment. Methods. 80 consecutive patients with active infective endocarditis (52 males, 28 females, mean age 59.2 years) were referred to our institution for surgical treatment. 78 patients underwent surgery, and 2 patients died before intervention. Results. Fifty patients had native valve endocarditis, 30 prosthetic valve involvement. Hospital mortality has been 10.2%. Three discharged patients (4.9%) died at an average 18-month followup. Endocarditis recurred in 4 (2 being S. aureus prosthetic tricuspid endocarditis in drug addicts). All patients who underwent valve repair or homograft implant were alive and free of recurrence. Conclusions. Our results suggest that with proper surgical treatment patients with active endocarditis discharged alive from hospital have a survival >90% at 18 months with a low recurrence rate.
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Rostagno et al. (2011) conducted a cohort in Active infective endocarditis (n=80). Surgical treatment was evaluated on Survival and recurrence rate. Surgical treatment for active infective endocarditis was associated with a 10.2% hospital mortality, with discharged patients achieving >90% survival and a low recurrence rate at 18 months.
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