Monoclonal antibody was raised against a tetrapeptide containing l-pyrenylalanine. The antibody bound the tetrapeptide as well as l-pyrenylalanine methyl ester, indicating that it recognizes the pyrenyl group. The antibody, however, did not bind d-pyrenylalanine methyl ester. This finding suggests a potentiality of monoclonal antibodies for chiral separations.
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Imaizumi et al. (1994) studied this question.
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