Tricuspid regurgitation: choosing the right treatment for the right patient at the right time

Benedetto Del Forno; Francesco Maisano; Ottavio Alfieri

doi:10.1093/ejcts/ezag244

October 19, 2026European Journal of Cardio-Thoracic Surgery

Tricuspid regurgitation: choosing the right treatment for the right patient at the right time

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Key result

Tricuspid regurgitation management requires individualized treatment selection based on patient characteristics and timing.

Key Points

To review clinical pathways and decision-making criteria for selecting appropriate surgical or transcatheter interventions and optimizing procedural timing in patients with tricuspid regurgitation.
Synthesizes current clinical evidence regarding the natural history and hemodynamics of tricuspid valve insufficiency.
Evaluates comparative therapeutic strategies, including medical therapy, open-heart surgical annuloplasty or replacement, and emerging transcatheter edge-to-edge and replacement devices.
Demonstrates that delaying intervention until severe right ventricular remodeling or end-stage organ dysfunction occurs significantly worsens surgical and transcatheter prognosis.
Identifies tailored patient selection based on valve anatomy, leaflet morphology, and ventricular function as critical for achieving durable repair and reducing mortality.

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Implication

Supports individualized tricuspid regurgitation timing; leaves open prospective validation of selection criteria.

Abstract

Benedetto Del Forno, Francesco Maisano, Ottavio Alfieri; Tricuspid regurgitation: choosing the right treatment for the right patient at the right time, Eur

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Cite This Study

Forno et al. (2026) studied this question. Optimal management of tricuspid regurgitation requires highly individualized treatment selection based on specific patient characteristics and appropriate timing.

synapsesocial.com/papers/6ad8a1e74fe90d57c13299d8 https://doi.org/10.1093/ejcts/ezag244

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Tricuspid regurgitation: choosing the right treatment for the right patient at the right time

Key Points

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Implication

Abstract

Discussion

Cite This Study

Tricuspid regurgitation: choosing the right treatment for the right patient at the right time

Key Points

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Implication

Abstract

Discussion

Cite This Study

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