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October 19, 2026Neuro-Oncology

Tuning CAR-T Cell Fitness Through Tonic Signaling in Diffuse Midline Glioma

S Z Winson Ho Rongze Lu

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Abstract

S Z Winson Ho, Rongze Olivia Lu; Tuning CAR-T Cell Fitness Through Tonic Signaling in Diffuse Midline Glioma, Neuro-Oncology, , noag250, https://doi.org/10

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Cite This Study

Ho et al. (2026) studied this question.

synapsesocial.com/papers/6ad9a741361370fd88dbbee8 https://doi.org/10.1093/neuonc/noag250

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A CAR-T Tonic Signaling Code Predicts Anti-Tumor Efficacy in Diffuse Midline GliomaOriginal Research · 2026
2A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma2025
3Abstract 5201: Tuning gated CAR-T cells for enhanced activity against acute myeloid leukemiaOriginal Research · 2026
4Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitnessOriginal Research · 2023 · 190 citations
5Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells2024 · 2 citations

More related papers

Abstract 6463: Longitudinal single-cell atlas of GD2-CAR T cell therapy in H3K27M-mutant diffuse midline glioma identifies humoral and cellular anti-CAR immunity2026
Abstract 3715: Epigenetic and signaling-based engineering enhances CAR-T cell function in oculo-cerebral lymphoma2026
Endogenous immune recruitment in glioblastoma CAR T therapy: cytokine, myeloid, and chemokine circuitry2026

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