Summary Tests of over 2000 pigs, with the blood group reagents Ac, Ap and 0, and the reagents Ha, Hb, He, Hd, He and Hc/c, confirmed that the H locus affects the expression of A and 0 antigens. The ‘exceptional’ phenotypes Ap and — were found in Ha homozygotes of Miniature pigs and in Hcd homozygotes of a semi‐inbred Landrace line. They were also found in unrelated pigs of other breeds, and moreover in some individuals with genotypes HaHcd, HabHcd, H‐H‐ and HaHab or HabHab. The mechanism of the effect of the H locus on the A phenotypes may consist in the interaction of certain, not yet completely defined, H genotypes, or in linkage of the H system with the hypothetical ‘S’ locus.
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A 1974 study studied this question.
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