Key result
Bystander CPR alone is insufficient to overcome the challenge of out-of-hospital cardiac arrest, which has a global incidence of approximately 50 per 100,000 person-years.
Out-of-hospital cardiac arrest remains a major healthcare challenge with low survival rates and a critical dependence on reducing the time from collapse to initial cardiopulmonary resuscitation.
Despite decades-long efforts by emergency medical services (EMS) to improve clinical outcomes after out-of-hospital cardiac arrest (OHCA), efficient strategies are still lacking. With a global incidence as high as around 50 per 100 000 person-years, a critically unfavourable relationship between no-flow duration (the time elapsed from collapse to the first cardiopulmonary resuscitation [CPR] measures) and survival, EMS response times that cannot be made faster, low survival rates, and poor neurological status among survivors despite advanced life support,1 OHCA still represents a substantial health-care challenge.
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Heidet et al. (2026) conducted an editorial in Out-of-hospital cardiac arrest (OHCA). Bystander cardiopulmonary resuscitation (CPR) was evaluated. Bystander CPR alone is insufficient to overcome the challenge of out-of-hospital cardiac arrest, which has a global incidence of approximately 50 per 100,000 person-years.
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